Low-Molecular-Weight Heparin vs Heparin in the Treatment of Patients With Pulmonary Embolism

Results: Of 200 patients with high-probability lung scan findings at study entry, none of the 97 who received lowmolecular-weight heparin had new episodes of venous thromboembolism compared with 7 (6.8%) of 103 patients who received intravenous heparin (95% confidence interval for the difference, 1.9%-11.7%; P = .01). Major bleeding associated with initial therapy occurred in 1 patient (1.0%) who was given low-molecularweight heparin and in 2 patients (1.9%) given intravenous heparin (95% confidence interval for the difference, −2.4% to 4.3%).